Exhibitors Search
GEMCRO Inc.
Booth no.
H50
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Exhibition
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|KOREA LIFE SCIENCE |
|---|---|
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Country
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| Korea, South |
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Address
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|201 Hyangdong-ro, Deogyang-gu, Goyang-si, Gyeonggi-do, Republic of Korea |
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Tel
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|+82-2-6677-6649 |
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Exhibits
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| Development of genetically engineered mice for preclinical efficacy verification of new drug development |
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Company Type
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| Biotech Venture / Startup , CRO / CMO Company |
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Exhibitor Information
GEMCRO is a biotechnology venture company specializing in the development of customized genetically engineered mouse (GEM) models using CRISPR/Cas9 technology.
Building on pioneering work in the generation of gene-edited mouse models using genome-editing technology (Nature Biotechnology, 2013; Genome Research, 2014), GEMCRO is developing advanced preclinical platform models designed to improve the probability of success in innovative drug development.
With expertise in knockout (KO), knock-in (KI), conditional knockout (cKO), and humanized mouse model development, GEMCRO provides a broad portfolio of models across multiple disease areas, including oncology, immunological disorders, and infectious diseases. We are also expanding collaborations to develop next-generation models with improved disease recapitulation, greater translational relevance to human biology, and enhanced predictability of therapeutic responses.
Building on pioneering work in the generation of gene-edited mouse models using genome-editing technology (Nature Biotechnology, 2013; Genome Research, 2014), GEMCRO is developing advanced preclinical platform models designed to improve the probability of success in innovative drug development.
With expertise in knockout (KO), knock-in (KI), conditional knockout (cKO), and humanized mouse model development, GEMCRO provides a broad portfolio of models across multiple disease areas, including oncology, immunological disorders, and infectious diseases. We are also expanding collaborations to develop next-generation models with improved disease recapitulation, greater translational relevance to human biology, and enhanced predictability of therapeutic responses.
Exhibit Description
1. Customized Genetically Engineered Mouse (GEM) Development: We develop GEM including knockout (KO), knock-in (KI), conditional knockout (cKO), and other customized models
2. Customized Experimental Cohort Supply: Using in vitro fertilization (IVF)-based breeding technology, we provide scalable production and supply of disease models, enabling researchers to secure appropriately sized and standardized experimental cohorts.
3. Representative Preclinical Models:
3-1) N2G Severe Immunodeficient Mouse
3-2) hiFcRn™ Humanized Antibody PK Model
3-3) hiACE2™ COVID-19 Infection Model
2. Customized Experimental Cohort Supply: Using in vitro fertilization (IVF)-based breeding technology, we provide scalable production and supply of disease models, enabling researchers to secure appropriately sized and standardized experimental cohorts.
3. Representative Preclinical Models:
3-1) N2G Severe Immunodeficient Mouse
3-2) hiFcRn™ Humanized Antibody PK Model
3-3) hiACE2™ COVID-19 Infection Model
Individual Exhibit/Technology Introduction (Detailed)
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Product Name : N2G mouse modelA severely immunodeficient mouse model generated by deleting the Prkdc and Il2rg genes in the NOD background, enabling engraftment of human-derived cells and tissues.
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Product Name : hiFcRn mouse modelA humanized FcRn mouse model generated using CRISPR/Cas9 technology, in which the mouse FcRn gene is replaced with the human FcRn gene, enabling evaluation of human antibody therapeutics.
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Product Name : hiACE2 mouse modelA humanized ACE2 mouse model generated using CRISPR/Cas9 technology, in which the mouse Ace2 gene is precisely replaced with the corresponding human ACE2 sequence, enabling susceptibility to SARS-CoV-2 infection.
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Product Name : Mouse models for human diseasesAs part of its commitment to providing disease model animals for a wide range of disease research and drug development applications, GEMCRO supplies major disease models for Alzheimer’s disease, Parkinson’s disease, cancer, diabetes, and other conditions. Our portfolio includes both proprietary models developed by GEMCRO and animal models transferred from the National Institute of Food and Drug Safety Evaluation (NIFDS) under the Ministry of Food and Drug Safety (MFDS). For more information, please visit our website.
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Product Name : GEM ProductionGEMCRO develops customized genetically engineered mouse (GEM) models using CRISPR/Cas-based genome editing technologies. We provide a wide range of models, including knockout, knock-in, conditional KO/KI, and humanized mice, tailored to specific research objectives. Our integrated services cover target gene analysis and model design, genome editing, founder screening, genotyping and sequence validation, and strain establishment. By combining advanced genome engineering with reproductive technologies, GEMCRO provides reliable animal models for disease research and preclinical drug development.
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Product Name : GEMGEMCRO provides integrated animal model solutions for drug development, from supplying preclinical models optimized for efficacy and pharmacology studies to developing customized genetically engineered mouse (GEM) models tailored to specific research needs.
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